Intense Overnight Sleeping Cream - Jumbo
Double up and save with this jumbo size of our intensive sleeping cream formulated with nutrient-rich ingredients and lipids to deliver essential moisture while you sleep. Formulated with plant squalane, kakadu plum and a specialized blend of plant-based triglycerides, it delivers hydration for brighter and plumper-looking skin.
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A staple in my routine
The formula fits nicely into my routine and leaves my skin feeling soft and refreshed.
Worth keeping around
A dependable part of my routine with a finish I enjoy using every day.

A new daily favorite
The texture feels comfortable and layers easily with the rest of my routine.
So easy to use
I like how simple this is to add to my everyday routine. The finish feels light and comfortable.
Lovely on my skin
This has become one of the products I reach for most often. It feels gentle and pleasant to use.
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Frequently Asked Questions
What are exosomes in skincare?
Naturium’s Multi-Active Exosome Serum features a vegan microalgae-derived biomimetic exosome, a plant-derived extracellular vesicle inspired by the skin’s natural renewal process. It’s formulated to help improve the look of skin firmness, elasticity, and resilience, working with your skin to support the appearance of a visibly renewed, more supple complexion.
What is the science behind exosomes as a skincare ingredient?
The science behind our Multi-Active Exosome Serum is built on testing and the results speak for themselves. Our microalgae-derived biomimetic exosome is backed by in vitro and in vivo testing, as well as clinical and consumer perception studies.
What makes our exosome ingredient different/is this Vegan?
Yes. The Multi-Active Exosome Serum is vegan and cruelty-free. Our serum uses a microalgae-derived biomimetic exosome, inspired by the skin’s natural renewal process.
How does a “biomimetic exosome” work on skin?
Our micro-algae biomimetic exosomes are plant-derived extracellular vesicles that work to help skin look visibly renewed, firmer and more supple. Hexapeptide-9, a biomimetic peptide, helps to improve the look of fine lines and wrinkles while antioxidants help to improve skin’s overall brightness and radiance.
How long until I see results from using Naturium's Multi-Active Exosome Serum?
In a consumer study of Naturium’s Multi-Active Exosome Serum:
• 91% agreed that skin instantly looks visibly renewed in a single use
• 94% saw a reduced look of fine lines and wrinkles in only 30 days of daily use
You may notice an immediate difference in how your skin looks and feels after the first application. With consistent daily use, the benefits continue to build improving the look of skin firmness, elasticity, and resilience over time, while skin appears calmer, more youthful-looking, and more supple with every use.
As with any skincare ingredient, individual results will vary based on skin type and routine consistency.